Week 4 of 2024 college football picks vs. spread, odds, lineups, trends: Vegas expert reveals top picks

Young quarterbacks will be in the spotlight when the Week 4 football schedule arrives. Sophomore Jackson Arnold and No. 15 Oklahoma took redshirt freshman Nico Iamaleava and No. 6 Tennessee in the marquee game on Saturday, with Week 4 college football odds via SportsLine consensus listing the Vols as 7-point road favorites. Redshirt freshman Arch Manning could make his first career start for top-ranked Texas with Quinn Ewers (oblique) sidelined. The Longhorns are huge 44.5 point favorites against UTSA.

Freshman Dylan Raiola and No. 22 Nebraska has a ranked matchup on Friday night as they take on No. 24 Illinois (+7.5). Which of these Week 4 football lineups should you watch? Before you lock in any Week 4 college football odds for those or any other games, be sure to check out the college football betting guide from legendary Vegas handicapper Bruce Marshall .

For years, Vegas-based Marshall was synonymous with The Gold Sheet, a popular sports magazine. With a background in sports and sports work while in college, Marshall joined TGS in 1981 when he was hired by the legendary Mort Olshan and served as editor-in-chief at many years.

A sought-after guest on many radio and television shows across the country, Bruce’s extensive editorial work has been featured in the Las Vegas Review-Journal, New York Post and many other places. He has won various disability awards and is working on several book projects.

Now, using his Tech Corner approach that examines all the latest trends and trends in college football, Marshall turns his attention to college football betting for Week 4 and reveal options for each matchup. Visit here to see each option.

Top college football predictions for Week 4

One of college football’s highest picks Marshall advocates for Week 4: He backs the No. 15 Oklahoma (+7) against the spread as the Sooners take on the Vols in Norman at 7:30 pm ET on Saturday.

Tennessee is undoubtedly hot to open the season as the Vols have been held to more than 20 points in their first three games. However, this is the first real start for Iamaleava, and it should be against a hostile crowd as they soon play their first SEC game.

The Vols covered just once on the road last year, while Oklahoma covered seven of its last nine at home overall. Marshall expects a competitive game and is favored to score a full seven points with OU, while backing the Over (57.5) as these teams are a combined 4-2 overall so far in 2024. See what other options you can choose. Here.

How to make college football picks for Week 4

Marshall has analyzed each matchup and found the scary 11-0 betting tips you need to know this week. Get betting analysis for every game on SportsLine.

So which college football picks can you pick with confidence, and what’s the scary tip you need to know about one of the biggest games of the week? Check out the latest college football rankings below, then visit SportsLine to see which teams are coming back, all from Vegas’ historic multi-handicap champion, and find out .

Week 4 of college football

Check out the full Week 4 college football picks, odds, predictions here

Thursday, September 19

South Alabama in the Appalachian region (-7.5, 64.5)

Friday, September 20

Stanford at Syracuse (-9, 57.5)

Illinois at Nebraska (-8.5, 43)

San Jose State at Washington State (-11.5, 55.5)

Saturday 21 September

North Carolina State at Clemson (-20.5, 46.5)

Florida at Mississippi (+6, 58.5)

Marshall at Ohio State (-39.5, 52.5)

Arkansas at Auburn (-3, 58)

USC at Michigan (+6, 46.5)

Utah at Oklahoma State (+2.5, 54)

Tennessee at Oklahoma (+7, 57.5)

Louisiana-Monroe at Texas (-44, 52.5)

Baylor at Colorado (-1.5, 53.5)

Kansas State at BYU (+7, 47.5)


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